CBCS Gothenburg is located at the Swedish NMR Centre at the University of Gothenburg. We offer consulting with compound screening and drug discovery, assay development, small molecule screening (phenotypic and target-based), and fragment-based screens using NMR spectroscopy. We also offer hit confirmation and guidance for hit molecule optimization and hit complex assessment: macromolecular target structure and dynamics.

Services at CBCS Gothenburg

Our Instrument park

• NMR spectrometers for fragment based screens: 800 MHz, 3 mm TCI probe; 700 MHz, 5 mm 19F probe; 600 MHz, 5 mm TCI, 19F and 1H detection optimized, cooled SampleJets

• NMR spectrometers for hit conformation with macromolecular targets: 400 – 900 MHz

• Pipetting robots: Bruker SamplePro Tube L., Single channel, four cooled positions; Agilent Bravo, 96 channels, one cooled position, shaker, magnet position; Opentrons OT-2, multiple dispense, Two single channel pipettes, two cooled positions,

• Plate reader (96), SpectraMax® iD5

• Cell culture lab, CO2 incubator, light microscope, centrifure, cell dispenser etc.

• Maybridge and Bionet small molecule libraries with NMR annotation. In total 1200 compounds.

• CBCS compounds libraries on demand.